A previous post on working with Aiptek and Wacom Graphire4 drawing tablets drew the following response from Garett Harnish:

While it isn't "out-of-the-box," here are instructions on how to get the Graphite4 working under linux.

The instructions are for a distribution I've never heard of before, zenwalk, but they seem to be generic enough that they should work on any distro.  The gist seems to be that the newest wacom drivers from sourceforge work.  This means that over time, they should be integrated into the distros and you won't have to do much to get it to work.

I haven't tried this yet (I can't even find the Wacom at the moment, though I know where the Aiptek is), so caveat reader.